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Gordons Chemists Launch a new Cardiovascular Screening Clinic
23 May 2014 12:19:30

CardioHealth NI – Give your arteries an MOT!

Gordons Chemists are pleased to offer a new cardiovascular screening clinic.
Statistics indicate that around 60% of the time in heart attack cases, a standard cholesterol or blood pressure test won’t have revealed anything out of the ordinary. Guidelines (published in 2007) from the European Society of Hypertension recommend measuring arterial stiffness in patients with arterial hypertension (high blood pressure).
Gordons Chemists are pleased to offer across Northern Ireland a cardiovascular screening clinic, using a state-of-the-art arteriograph. CardioHealth NI is the first and only company in Northern Ireland that uses an arteriograph; a session with CardioHealth NI at one of our cardiovascular screening clinics is priced at only £50.
A cardiovascular screening using an arteriograph reveals much more than a typical blood pressure or cholesterol test will. By offering this cardiovascular screening clinic, we allow the patient to have a better understanding of the health of their arteries. As such they can make the decision to take control of their cardiovascular health – hopefully reducing the incidence or severity of heart attack, stroke or high blood pressure.
In addition to identifying underlying health problems, the screening includes recommendations on diet and natural health solutions. A detailed report allows the patient to consult with their GP or medical professional in order to seek further advice and treatment, based on the findings of the screening.
The cardiovascular screening clinic is suitable for anyone aged 16 years and over, or anyone with a family history of heart disease, kidney disease or diabetes. It’s also suitable for anyone who drinks alcohol or smokes, is overweight, or participates in (or is returning to) a sport.

About the Arteriograph
An arteriograph is a sophisticated instrument used for detecting changes to the artery walls. The arteriograph uses a cuff that contains special pressure sensors.
These pressure sensors are designed to detect the Pulse Wave (pressure wave) that leaves the heart as it contracts. When the pulse wave reaches the end of the arterial system, it is then reflected back towards the heart. Three key measurements are taken from this pulse wave.
An arteriograph reveals damage to the heart and arteries that a standard blood pressure or cholesterol test will not. It measures parameters that indicate if the patient might at risk of heart attack or stroke, including:
Central Systolic Blood Pressure
This in effect measures blood pressure, at the heart. Studies indicate that this is of greater value than measuring blood pressure on the arm.
Brachial Augmentation
This reveals early damage to, and clogging up of, your smaller arteries. When arterial clogging begins, it occurs firstly in the small arteries of the hands and feet. This can be measured and it indicates the degree of clogging and the damage to the inner lining of your smaller arteries.
Pulse Wave Velocity
The speed of the pressure wave described above is measured over a given distance. An increased speed indicates a clogging of the arteries. There is a direct correlation between this, and an increased risk of heart attack/stroke. The reading is often found to be abnormal in patients with kidney disease, diabetes, sufferers of rheumatoid arthritis, and smokers.
The Arteriograph is a new, easy-to-use, and time-effective method for assessing arterial stiffness. Prior to the arteriograph, there were (and still are) two invasive methods used within a hospital setting: the tonometric and piezo-electronic systems (SphygmoCor and Complior).
An arteriograph is not intended as a replacement for these. Instead, the device is intended for use as a quick, affordable and non-invasive means of diagnosing an underlying condition that the patient may not be aware of. Clinical trials (see below for details) reveal that an arteriograph gives accurate results (which are comparable to the two systems mentioned).
The main advantage of using an arteriograph is that it offers a quick and affordable assessment, using only the upper arm.
Other methods involve a detailed examination and take time to complete. Typically, these (due to the time and expense involved in completing a screening) aren’t readily available at the request of a patient.
CardioHealth NI’s cardiovascular screening clinics offer the patient the opportunity to have a detailed and accurate assessment of their cardiovascular system completed – at a relatively low price, in a location close to them, in just half an hour.
Upcoming clinic detail can be obtained by emailing: info@gordonsdirect.com

Clinical Evidence
Publications on the validation of the Arteriograph device:
•Baulmann, J. et al.
•"A new oscillometric method for assessment of arterial stiffness: comparison with tonometric and piezo-electronic methods"
•J Hypertens 2008, 26:523-528
•http://www.arteriograph.hu/downloads/pdf/Baulmann%20validation-J-Hypert%2708March-Cover.pdf

•Jatoi, N.A., et al.
•“Assessment of arterial stiffness in hypertension: comparison of oscillometric (Arteriograph), piezoelectronic (Complior) and tonometric (SphygmoCor) techniques”
•J Hypertens 2009, 27:2186–2191
•http://www.arteriograph.hu/downloads/pdf/Mahmud-Feely-Compl-Sphygm-Art-JHypert-Oct%2709.pdf

•Boutouyrie P, Revera M and Parati G.
•“Obtaining arterial stiffness indices from simple arm cuff measurements: the holy grail?”
•J Hypertension 2009; 27:2159-2161
•http://www.arteriograph.hu/downloads/pdf/Boutouyrie-Editorial-JHypert-Oct%2709.pdf

•Rajzer MW, Wojciechowska W, Klocek M, Palka I, Brzozowska-Kiszka M, Kawecka-Jaszcz K.
•“Comparison of aortic pulse wave velocity measured by three techniques: Complior, SphygmoCor and Arteriograph.”
•J Hypertens 2008; 26:2001-7
•http://www.arteriograph.hu/downloads/pdf/Marek%20Rajzer%20comp%20study%20with%20ARG.pdf

•Horváth, G.I. et al
•“Invasive validation of a new oscillometric device (Arteriograph) for measuring augmentation index, central blood pressure and aortic pulse wave velocity”
•J Hypertens 2010, 28:2068–2075
•http://www.arteriograph.hu/downloads/pdf/Invasive%20validation%20JoH%202010%2028.pdf

•Parati G, Buyzere de M
•“Evaluating aortic stiffness through an arm cuff oscillometric device: is validation against invasive measurements enough?"
•Journal of Hypertension 2010, 28:2003–2006
•http://www.arteriograph.hu/downloads/pdf/Parati%20Editorial%20Comment%20on%20invasive%20validation.pdf
[PR]
by suwataisya | 2014-07-09 15:15 | 動脈硬化

ESC2013 Arteriograph 4,000以上の患者データ発表


[PR]
by suwataisya | 2014-06-23 15:56 | 動脈硬化

Arterial Stiffness

Invasive validation of a new oscillometric device
(Arteriograph) for measuring augmentation index, central
blood pressure and aortic pulse wave velocity
Iva´n G. Horva´ tha, A´ da´m Ne´metha, Zso´ fia Lenkeya, Nicola Alessandrib,
Fabrizio Tufanob, Pa´ l Kisa, Bala´ zs Gasznera and Attila Czira´ kia
Background The importance of measuring aortic pulse
wave velocity (PWVao), aortic augmentation index (Aix) and
central systolic blood pressure (SBPao) has been shown
under different clinical conditions; however, information on
these parameters is hard to obtain. The aim of this study
was to evaluate the accuracy of a new, easily applicable
oscillometric device (Arteriograph), determining these
parameters simultaneously, against invasive
measurements.
Methods Aortic Aix, SBPao and PWVao were measured
invasively during cardiac catheterization in 16, 55 and
22 cases, respectively, and compared with the values
measured by the Arteriograph.
Results We found strong correlation between the invasively
measured aortic Aix and the oscillometrically measured
brachial Aix on either beat-to-beat or mean value per patient
basis (rU0.9, P<0.001; rU0.94, P<0.001), which allowed
the noninvasive calculation of the aortic Aix without using
generalized transfer function. Similarly strong correlation
(rU0.95, P<0.001) was found between the invasively
measured and the noninvasively calculated central SBPao;
furthermore, the BHS assessment of the paired differences
fulfilled the ‘B’ grading. The PWVao values measured
invasively and by Arteriograph were 9.41W1.8 m/s and
[PR]
by suwataisya | 2014-05-28 17:32 | 動脈硬化

Arterial Stiffness

Comparison of aortic pulse wave velocity measured by three
techniques: Complior, SphygmoCor and Arteriograph
Marek W. Rajzer, Wiktoria Wojciechowska, Marek Klocek, Ilona Palka,
Małgorzata Brzozowska-Kiszka and Kalina Kawecka-Jaszcz
Background New 2007 European Society of Hypertension
guidelines recommend measuring arterial stiffness in
patients with arterial hypertension, suggesting a
carotid–femoral pulse wave velocity over 12 m/s as an
estimate of subclinical organ damage. Considering this
cutoff point, it is worth exploring whether or not there are
significant differences in results obtained using various
techniques for measuring aortic pulse wave velocity. The
aim of the study was to compare aortic pulse wave velocity
measurements using Complior, SphygmoCor, and
Arteriograph devices, and to assess the effect of pulse wave
transit time and traveled distance on pulse wave velocity
values.
Methods Aortic pulse wave velocity was measured on a
single visit, using these devices, in randomized order, in a
group of 64 patients with grade 1 or 2 arterial hypertension.
Results Aortic pulse wave velocity measured using
Complior (10.1W1.7 m/s) was significantly higher than that
obtained using SphygmoCor (8.1W1.1 m/s) or Arteriograph
(8.6W1.3 m/s). No differences were noted between pulse
wave velocity measurements using SphygmoCor and
Arteriograph. Between-method comparison revealed that
differences in traveled distance were significant: Complior
[PR]
by suwataisya | 2014-05-28 17:31 | 動脈硬化

Arterial Stiffness

Assessment of arterial stiffness in hypertension: comparison
of oscillometric (Arteriograph), piezoelectronic (Complior)
and tonometric (SphygmoCor) techniquesM
Noor A. Jatoi, Azra Mahmud, Kathleen Bennett and John Feely1
Background Arterial stiffness, measured as aortic
pulse wave velocity (PWV), and wave reflection,
measured as augmentation index (AIx), are independent
predictors for total and cardiovascular morbidity and
mortality. The aim of this study was to compare a new
device, based on oscillometric pressure curves
(Arteriograph), which simultaneously measures PWV and
AIx, with standard techniques for measuring PWV
(Complior) and AIx (SphygmoCor) in untreated
hypertensive patients.
Methods We compared PWV and AIx measured using the
Arteriograph with corresponding Complior and
SphygmoCor measurements in 254 untreated hypertensive
patients, age 48W14 years (meanWSD, range 17–85
years).
Results Arteriograph PWV and AIx were closely related with
Complior (rU0.60, P<0.001) and SphygmoCor (rU0.89,
P<0.001), respectively. Using stepwise regression analysis,
the independent determinants of Arteriograph PWV were
age, mean arterial pressure, heart rate and sex (r2U0.44,
P<0.0001) and for AIx were age, weight, mean arterial
pressure, heart rate and sex (r2U0.65, P<0.0001). The bias
between the different techniques was determined by age
and sex for PWV and age, body weight, sex, heart rate and
[PR]
by suwataisya | 2014-05-28 17:30 | 動脈硬化

Arterial Stiffness

Evaluating aortic stiffness through an arm cuff oscillometric
device: is validation against invasive measurements enough?
Gianfranco Paratia,b and Marc De Buyzerec
Journal of Hypertension 2010, 28:2003–2006
aDepartment of Cardiology, S. Luca Hospital, IRCCS, Istituto Auxologico Italiano,
bDepartment of Clinical Medicine and Prevention, University of Milano-Bicocca,
Milan, Italy and cDepartment of Heart and Vessel Diseases, University Hospital
Ghent, Belgium
Correspondence to Professor Gianfranco Parati, MD, Department of Cardiology,
Istituto Scientifico Ospedale San Luca, Istituto Auxologico Italiano, p.zza Brescia,
20, Milan 20149, Italy
Tel: +39 02 6191 12980; fax: +39 02 6191 12956;
e-mail: gianfranco.parati@unimib.it
See original paper on page 2068
Introduction
Following the 2006 expert consensus document of the
European Network for Noninvasive Investigation of
Large Arteries [1], arterial stiffness and central pressure
measurements should be considered as recommended
tests for the evaluation of cardiovascular risk, particularly
in patients in whom target organ damage is
not discovered by routine investigations. Within the
area of noninvasive methods, pulse wave recording
and analysis either from central (ascending aorta, carotid
artery) or peripheral (radial artery) sites have become
popular, particularly after the release of dedicated commercial
devices [2]. Theoretically, pulse wave analysis
[PR]
by suwataisya | 2014-05-28 17:29 | 動脈硬化

Arterial Stiffness

Obtaining arterial stiffness indices from simple arm cuff
measurements: the holy grail?
Pierre Boutouyriea,b, Miriam Reverac,d and Gianfranco Paratic,d
Journal of Hypertension 2009, 27:2159–2161
aUniversite´ Paris Descartes; INSERM, U970, bDepartment of Pharmacology,
Assistance Publique-Hoˆ pitaux de Paris, Hoˆ pital Europe´en Georges Pompidou,
Paris, France, cDepartment of Clinical Medicine and Prevention, Milano-Bicocca
University and dDepartment of Cardiology, IRCCS San Luca Hospital, Istituto
Auxologico Italiano, Milan, Italy
Correspondence to Professor Gianfranco Parati, MD, Department of Cardiology,
San Luca Hospital, Istituto Auxologico Italiano, Via Spagnoletto 3, 20149 Milan,
Italy
Tel: +39 02 6191 12890; fax: +39 02 6191 12956;
e-mail: gianfranco.parati@unimib.it
See original paper on page 2186
Precise assessment of cardiovascular risk factors is a
necessary step for the identification of patients at high
risk of developing cardiovascular events. When setting
the operating curve of the risk function, measurement of
blood glucose and lipids, estimation of blood pressure
(BP) levels, identification of smoking status, and assessment
of existing organ damage represent the main determinants
of the tendency to develop cardiac and vascular
problems over and above the impact of nonmodifiable
factors such as age and sex. Each of these classical risk
factors is included in a risk function specific to a given
population and aimed at yielding absolute quantitative
values of cardiovascular risk [1,2]. Such an approach
[PR]
by suwataisya | 2014-05-28 17:28 | 動脈硬化

Arterial Stiffness

Assessment of arterial stiffness in hypertension: comparison of oscillometric (Arteriograph), piezoelectronic (Complior) and tonometric (SphygmoCor) techniques.
Abstract
BACKGROUND
Arterial stiffness, measured as aortic pulse wave velocity (PWV), and wave reflection, measured as augmentation index (AIx), are independent predictors for total and cardiovascular morbidity and mortality. The aim of this study was to compare a new device, based on oscillometric pressure curves (Arteriograph), which simultaneously measures PWV and AIx, with standard techniques for measuring PWV (Complior) and AIx (SphygmoCor) in untreated hypertensive patients.
METHODS
We compared PWV and AIx measured using the Arteriograph with corresponding Complior and SphygmoCor measurements in 254 untreated hypertensive patients, age 48 +/- 14 years (mean +/- SD, range 17-85 years).
RESULTS
Arteriograph PWV and AIx were closely related with Complior (r = 0.60, P < 0.001) and SphygmoCor (r = 0.89, P < 0.001), respectively. Using stepwise regression analysis, the independent determinants of Arteriograph PWV were age, mean arterial pressure, heart rate and sex (r(2) = 0.44, P < 0.0001) and for AIx were age, weight, mean arterial pressure, heart rate and sex (r(2) = 0.65, P < 0.0001). The bias between the different techniques was determined by age and sex for PWV and age, body weight, sex, heart rate and mean arterial pressure for AIx. Bland-Altman plots showed that although the techniques were closely related, the limits of agreement were wide.
CONCLUSION
Although Arteriograph values and the determinants of PWV and AIx are in close agreement with corresponding parameters obtained by Complior and SphygmoCor, respectively, the techniques are not interchangeable.
[PR]
by suwataisya | 2014-05-28 17:27 | 動脈硬化

Arterial Stiffness

Abstracts of the American Society of Hypertension, Inc.
28th Annual Scientific Meeting and Exposition, San Francisco, USA May 15-18, 2013
The Journal of Clinical Hypertension, 2013, Volume 15,
May 2013 Abstract Supplement
28th Annual Scientific Meeting and Exposition
San Francisco, USA May 15-18, 2013.
________________________________________
Acute Coronary Syndrome Patients: How Stiff are their Arteries?
Deaconu Alexandru Ioan 1 , Tautu Oana Florentina 1 , Fruntelata Ana Gabriela 2 , Dorobantu Maria 1
1 Emergency Hospital of Bucharest, Bucharest, Romania;
2 Monza Cardiovascular Center, Bucharest, Romania
Several non-invasive methods are currently used to assess vascular stiffness. Pulse wave velocity (PWV) and the augmentation index (AIx) are the two major non-invasive methods of assessing arterial stiffness. A large amount of evidence indicates that carotid-femoral PWV is an intermediate endpoint for cardiovascular (CV) events, either fatal or non-fatal. Central AIx and pulse pressure have shown an independent predictive value for CV events in hypertensives and patients with coronary disease. Studies of arterial stiffness in patients with cardiovascular emergencies and acute coronary syndromes, respectively, are missing.
We performed measurements of arterial stiffness parameters using the TensioMed Arteriograph in 34 patients admitted for acute coronary syndromes (ACS), 24 hours after admission. The study group included 28 males (82.4%) and mean age was 61.7 ± 14.07 years. Arterial stiffness parameters as aortic PWV, aortic AIx, central systolic blood pressure (aortic SBP), central pulse pressure (aortic PP) were analyzed in relation to clinical, historical and paraclinical parameters in order to describe particularities in this patient population. We compared the results with an age and sex adjusted population of 34 controls randomly selected from the most recent Romanian cross-populational statistical survey, SEPHAR II.
In our group, 45.7% of patients were hypertensive and 37.1% were diabetic. Most of the patients were on treatment with ACE inhibitors (91.4%) and beta-blockers (80%), while 71.1% were on intravenous or oral nitrates. Mean stiffness parameters in this group were: aortic AIx=28.51 + 10.81, with only 14.8% of patients showing normal values; aortic PWV = 9.71 ± 1.82 m/s; aortic SBP = 121.71 ± 21.07 mm Hg; aortic PP = 44.39 ± 13.74 mm Hg. No correlations were identified in this small group between arterial stiffness parameters and treatment, history of hypertension or diabetes, type of ACS and angiographic coronary anatomy. While aortic AIx was clearly abnormal, reflecting changes in endothelial function and waves’ reflection, the other parameters of arterial stiffness were not different from other patient populations.
Aortic AIx is abnormally increased in patients with acute coronary syndromes. Parameters of arterial stiffness in patients with ACS are not related to treatment, type of coronary disease or previous patient history.
[PR]
by suwataisya | 2014-05-28 17:26 | 動脈硬化

Arterial Stiffness

Invasive Validation of Arteriograph Estimates of Central Blood Pressure in Patients With Type 2 Diabetes
1.Niklas Blach Rossen1,2,
2.Esben Laugesen2,
3.Christian Daugaard Peters3,
4.Eva Ebbehøj2,
5.Søren Tang Knudsen2,
6.Per Løgstrup Poulsen2,
7.Hans Erik Bøtker4 and
8.Klavs Würgler Hansen1
+ Author Affiliations
1.1 Department of Medicine, Silkeborg Regional Hospital, Silkeborg, Denmark;
2.2 Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark;
3.3 Department of Renal Medicine, Aarhus University Hospital, Aarhus, Denmark;
4.4 Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark.
1.Correspondence: Niklas Blach Rossen (niklas.rossen@rm.dk).
Received April 15, 2013.
Revision received August 6, 2013.
Accepted August 7, 2013.
Abstract
BACKGROUND Central blood pressure (BP) has attracted increasing interest because of a potential superiority over brachial BP in predicting cardiovascular morbidity and mortality. Several devices estimating central BP noninvasively are now available. The aim of our study was to determine the validity of the Arteriograph, a brachial cuff-based, oscillometric device, in patients with type 2 diabetes.
METHODS We measured central BP invasively and compared it with the Arteriograph-estimated values in 22 type 2 diabetic patients referred to elective coronary angiography.
RESULTS The difference (invasively measured BP minus Arteriograph-estimated BP) in central systolic BP (SBP) was 4.4±8.7mm Hg (P = 0.03). The limits of agreement were ±17.1mm Hg.
CONCLUSIONS Compared with invasively measured central SBP, we found a systematic underestimation by the Arteriograph. However, the limits of agreement were similar to the previous Arteriograph validation study and to the invasive validation studies of other brachial cuff-based, oscillometric devices. A limitation in our study was the large number of patients (n = 14 of 36) in which the Arteriograph was unable to analyze the pressure curves. In a research setting, the Arteriograph seems applicable in patients with ty
[PR]
by suwataisya | 2014-05-28 17:25 | 動脈硬化


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