クラウド カーディオロジ スマホ 富士の国 心電図伝送

スキー&スノーボード2004-2005

Arterial Stiffness

Clin Cardiol. 2012 Jan;35(1):26-31. doi: 10.1002/clc.20999. Epub 2011 Nov 14.
Comparison of aortic and carotid arterial stiffness parameters in patients with verified coronary artery disease.
Gaszner B, Lenkey Z, Illyés M, Sárszegi Z, Horváth IG, Magyari B, Molnár F, Kónyi A, Cziráki A.
Source
Heart Institute, Faculty of Medicine, University of Pécs, Hungary.
Abstract
BACKGROUND:
Arterial stiffness parameters are commonly used to determine the development of atherosclerotic disease. The independent predictive value of aortic stiffness has been demonstrated for coronary events.
HYPOTHESIS:
The aim of our study was to compare regional and local arterial functional parameters measured by 2 different noninvasive methods in patients with verified coronary artery disease (CAD). We also compared and contrasted these stiffness parameters to the coronary SYNTAX score in patients who had undergone coronary angiography.
METHODS:
In this study, 125 CAD patients were involved, and similar noninvasive measurements were performed on 125 healthy subjects. The regional velocity of the aortic pulse wave (PWVao) was measured by a novel oscillometric device, and the common carotid artery was studied by a Doppler echo-tracking system to determine the local carotid pulse wave velocity (PWVcar). The augmentation index (AIx), which varies proportionately with the resistance of the small arteries, was recorded simultaneously.
RESULTS:
In the CAD group, the PWVao and aortic augmentation index (Alxao) values increased significantly (10.1 ± 2.3 m/sec and 34.2% ± 14.6%) compared to the control group (9.6 ± 1.5 m/sec and 30.9% ± 12%; P < 0.05). We observed similar significant increases in the local stiffness parameters (PWVcar and carotid augmentation index [Alxcar]) in patients with verified CAD. Further, we found a strong correlation for PWV and AIx values that were measured with the Arteriograph and those obtained using the echo-tracking method (r = 0.57, P < 0.001 for PWV; and r = 0.65, P < 0.001 for AIx values).
CONCLUSIONS:
Our results indicate that local and regional arterial stiffness parameters provide similar information on impaired arterial stiffening in patients with verified CAD.
© 2011 Wiley Periodicals, Inc.
[PR]
# by suwataisya | 2014-05-28 17:16 | 動脈硬化

Arterial Stiffness

Hypertension Research (2011) 34, 202–208; doi:10.1038/hr.2010.196; published online 21 October 2010
Can arterial stiffness parameters be measured in the sitting position?
Jens Nürnberger1, Rene Michalski2, Tobias R Türk2, Anabelle Opazo Saez1, Oliver Witzke2 and Andreas Kribben2
1.1Department of Nephrology and Dialysis, HELIOS Kliniken Schwerin, Wismarsche Straße, Schwerin, Germany
2.2Department of Nephrology, University Hospital Essen, University Essen-Duisburg, Hufelandstraße, Essen, Germany
Correspondence: Dr J Nürnberger, Department of Nephrology, HELIOS Kliniken Schwerin, Wismarsche Straße 393-397, Schwerin 19049, Germany. E-mail: jens.nuernberger@uni-due.de
Received 2 May 2010; Revised 25 July 2010; Accepted 31 July 2010; Published online 21 October 2010.
Top of page
Abstract
Despite the introduction of arterial stiffness measurements in the European recommendation, pulse wave velocity (PWV) and augmentation index (AI) are still not used routinely in clinical practice. It would be of advantage if such measurements were done in the sitting position as is done for blood pressure. The aim of this study was to evaluate whether there is a difference in stiffness parameters in sitting vs. supine position. Arterial stiffness was measured in 24 healthy volunteers and 20 patients with cardiovascular disease using three different devices: SphygmoCor (Atcor Medical, Sydney, Australia), Arteriograph (TensioMed, Budapest, Hungary) and Vascular Explorer (Enverdis, Jena, Germany). Three measurements were performed in supine position followed by three measurements in sitting position. Methods were compared using correlation and Bland–Altman analysis. There was a significant correlation between PWV in supine and sitting position (Arteriograph: P<0.0001, r=0.93; Vascular Explorer; P<0.0001, r=0.87). There were significant correlations between AI sitting and AI supine using Arteriograph (P<0.0001, r=0.97), Vascular Explorer (P<0.0001, r=0.98) and SphygmoCor (P<0.0001, r=0.96). When analyzed by Bland–Altman, PWV and AI measurements in supine vs. sitting showed good agreement. There was no significant difference in PWV obtained with the three different devices (Arteriograph 7.5±1.6 m s−1, Vascular Explorer 7.3±0.9 m s−1, SphygmoCor 7.0±1.8 m s−1). AI was significantly higher using the Arteriograph (17.6±15.0%) than Vascular Explorer and SphygmoCor (10.2±15.1% and 10.3±18.1%, respectively). The close agreement between sitting and supine measurements suggests that both PWV and AI can be reliably measured in the sitting position.
Keywords:
arterial stiffness; augmentation index; PWV; pluse wave velocity
[PR]
# by suwataisya | 2014-05-28 17:15 | 動脈硬化

Arterial Stiffness

Renal Denervation Improves Blood Pressure And Arterial Stiffness
Published: August 27, 2012.
By European Society of Cardiology
http://www.escardio.org

Munich, Germany – August 27 2012: Renal denervation improves blood pressure and arterial stiffness in patients with therapy resistant hypertension, according to research presented at ESC Congress 2012 by Mr Klaas Franzen from the University Hospital of Schleswig-Holstein. The findings suggest that renal denervation regenerates blood vessels and could reduce cardiovascular events.
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Malignant arterial hypertension was historically treated with surgical thoracolumbar splanchnicectomy, a type of sympathectomy treatment that was introduced in 1938. "A significant reduction in blood pressure response was observed in at least half of the patients who underwent splanchnicectomy," said Mr Franzen. "But the treatment led to severe adverse events such as orthostatic hypotension, anhidrosis and intestinal disturbances. After the discovery of effective antihypertensive drugs, splanchnicectomy became neglected and disregarded over time."
In 2009 the concept of sympathectomy was reintroduced with intravasal catheter-based percutaneous renal sympathetic denervation (RDN) used in patients suffering from resistant arterial hypertension. Recent publications have shown that RDN significantly lowers systolic and diastolic peripheral brachial blood pressure by 32/12 mmHg after 6 months.
Mr Franzen said: "RDN with radiofrequency energy has several important advantages over surgical splanchnicectomy: it is a minimally invasive procedure without significant systematic side effects, it is well tolerated, and recovery times are short."
Arterial hypertension can irrevocably harm blood vessels in the short and long term, subsequently leading to increased aortic/arterial stiffness and arteriosclerosis. "Since central aortic pressures and arterial stiffness are much better predictors for future cardiovascular events than peripheral pressures we focused the present study on the effects of RDN on central hemodynamics and arterial stiffness," said Mr Franzen.
The researchers studied 21 patients with therapy resistant hypertension (61.9% men; mean age 64 years; 5.0±1.3 antihypertensive drugs) and 6 controls (83.3% men; mean age 57 years; 4.3±2.3 antihypertensive drugs). The inclusion criteria were: (i) use of >3 antihypertensive drugs, (ii) peripheral blood pressure at baseline ≥150 mmHg, and (iii) exclusion of secondary hypertension and anatomical abnormalities of the renal arteries.
RDN was performed with an RDN radiofrequency ablation catheter system (1). Central hemodynamics and arterial stiffness, i.e. pulse wave velocity (PWV), were recorded with an Arteriograph device (2). Measurements were performed at baseline, and 3 and 6 months after the intervention.
RDN led to an improvement in all parameters compared to baseline. Peripheral systolic blood pressure improved by 7.6% (145 mmHg versus 156 mmHg, p<0.05) after 3 months and by 5.4% (148 mmHg versus 156 mmHg, p<0.05) after 6 months. Central systolic blood pressure improved by 9.5% (147 mmHg versus 161 mmHg, p<0.01) after 3 months and by 6.6% (151 mmHg versus 161 mmHg, p<0.05) after 6 months. Most importantly, PWV improved significantly, both at 3 months (9.4±1.2 m/s versus 10.9±1.8 m/s, p<0.01) and 6 months (9.7±1.8 m/s versus 10.9±1.8 m/s, p<0.01). Univariate analysis of variance (f-test) showed that the improvement of PWV was, at least in part, blood pressure independent.
In controls no significant changes in blood pressure values or PWV were observed.
"Besides peripheral blood pressures, RDN improved central blood pressures and arterial stiffness, i.e. PWV," said Mr Franzen. "According to age adjusted reference values, the improvement of approximately 1m/s PWV observed in our study could be interpreted as a blood vessel rejuvenation of almost 10 years. This suggests that RDN might be a fountain of youth for blood vessels in patients with therapy resistant hypertension."
He added: "Further studies are needed to determine whether the benefits of RDN translate into a reduced risk of cardiovascular events."
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# by suwataisya | 2014-05-28 17:13 | 動脈硬化

アルテリオグラフ

Arteriograph






























[PR]
# by suwataisya | 2014-05-28 17:00 | 動脈硬化

新発売 ワイヤレス 携帯 動脈硬化指標計測計

地方販売代理店募集

http://homepage2.nifty.com/medicalteknika/tensiomedguide/

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[PR]
# by suwataisya | 2014-04-24 09:29 | 動脈硬化

12誘導心電図伝送を考える会



























[PR]
# by suwataisya | 2014-04-12 20:43 | 循環器

日本循環器学会2014で始まった新しい12誘導心電図の世界





[PR]
# by suwataisya | 2014-04-12 20:39 | 循環器

新しい12誘導心電図の世界が始まりました


[PR]
# by suwataisya | 2014-04-12 20:37 | 循環器

心臓リハビリ用ラブテック社12誘導心電図システム










[PR]
# by suwataisya | 2014-04-12 20:33 | 循環器

日本を誤って導いてきた日本の中の犯罪者は誰か


[PR]
# by suwataisya | 2014-01-05 15:21 | 医師会


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